ICMR report names samosas, chips among foods triggering diabetes epidemic in India

A groundbreaking clinical trial by the Indian Council of Medical Research (ICMR) has unveiled a significant link between ultra-processed and fried foods rich in Advanced Glycation End-products (AGEs) and India’s escalating diabetes crisis. This pioneering study, conducted by the Madras Diabetes Research Foundation, an ICMR Centre for Advanced Research in Diabetes, highlights the potential of low-AGE diets in mitigating diabetes risk. The study was published last week in the International Journal of Food Sciences and Nutrition.
The research, funded by the Department of Biotechnology, underscores the detrimental impact of diets high in AGEs, which include red meat, french fries, bakery products, parathas, samosas, and sugary foods. AGEs are harmful compounds formed through glycation, a process where proteins or lipids are modified by sugars. Accumulation of AGEs is linked to various health issues, including inflammation, oxidative stress, insulin resistance, and cellular damage.
The 12-week study involved 38 overweight and obese adults with a Body Mass Index (BMI) of 23 or higher. Researchers compared the effects of two diets: one high in AGEs and the other low in AGEs. Participants on the low-AGE diet demonstrated improved insulin sensitivity and lower blood sugar levels, while those on the high-AGE diet exhibited elevated AGE levels and increased inflammation.
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